ncRNA name | MCP-1 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinal neuronal cells |
Methods | immunohistochemistry, RT-PCR, Western blot, MTT assay, siRNA transfection, transwell assay, immunofluorescence, Chemotaxis assay, ELISA |
Expression pattern | associated |
Functional description | Retinal neurons that were pre-exposed to AGEs and an MCP-1 antibody or MCP-1 knockdown displayed greatly reduced microglial migration and TNF-α secretion. |
PubMed ID | 23010641 |
Year | 2012 |
Title | Upregulation of retinal neuronal MCP-1 in the rodent model of diabetic retinopathy and its function in vitro. |
Drug-related ncRNA | NO |
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